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. 2022 Feb 10;11:662723. doi: 10.3389/fonc.2021.662723

Figure 1.

Figure 1

TREM-1 is expressed on peripheral myeloid-derived suppressor cells (MDSC) subsets, tumor-infiltrating MDSC, and tumor-associated macrophages in tumor-bearing mice. (A) TREM-1 expression on splenic granulocytic MDSC (PMN-MDSC) and monocytic MDSC (Mo-MDSC) from naïve or tumor-bearing mice 21 days after 4T1 inoculation. (B) TREM-1 levels on tumor-derived Mo-MDSC 0, 7, 15, and 21 days after the 4T1 tumor challenge. *p < 0.05 relative to naïve mice, **p < 0.0. (C) TREM-1 expression on PMN-MDSC, Mo-MDSC, and tumor-associated macrophages isolated from tumors of tumor-bearing mice 21 days after 4T1 injection. One representative histogram is shown for each population out of more than three independent experiments.