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. 2022 Feb 23;12(2):e053936. doi: 10.1136/bmjopen-2021-053936

Table 2.

Association between genetic risk and risk of incident dementia

Predictor Model 1 Model 2
HR (95% CI) P value HR (95% CI) P value
Intermediate genetic risk versus low 1.56 (1.36 to 1.79) <0.001 1.49 (1.28 to 1.73) <0.001
High genetic risk versus low 1.79 (1.56 to 2.04) <0.001 1.71 (1.47 to 1.98) <0.001
Observations 155 063 139 345

Model 1. Adjusted for age and sex.

Model 2. Adjusted for age, sex, education, social deprivation, health behaviours, long-term illness, depressive symptoms and 10 principal components.

The values are HR and 95% CI.