Table 1.
Characteristics of U.S. Veterans with incident idiopathic pulmonary fibrosis (2010–2019)
| IPF Cohort |
||||
|---|---|---|---|---|
| Broad Case Definition | Narrow Case Definition | Control Population* | ||
| Total cases (n) | 139,116 | 82,557 | 10,650,206 | |
| Demographics | ||||
| Mean age at diagnosis in yr, (SD) | 70.7 (11.8) | 70.2 (11.0) | 61.5 (18.9) | |
| Sex, n (%) | ||||
| Male | 129,598 (93%) | 76,779 (93%) | 9,767,864 (91%) | |
| Female | 9,513 (7%) | 5,776 (7%) | 918,867 (9%) | |
| Race, n (%) | ||||
| White | 108,071 (78%) | 64,435 (78%) | 7,068,839 (66%) | |
| Black or African American | 14,338 (10%) | 8,989 (11%) | 1,479,129 (14%) | |
| Asian/Native Hawaiian or Pacific Islander/American Indian | 2,472 (2%) | 1,468 (2%) | 264,775 (3%) | |
| Unknown | 14,235 (10%) | 7,665 (9%) | 1,874,966 (18%) | |
| Ethnicity, n (%) | ||||
| Hispanic or Latino | 5,651 (4%) | 3,544 (4%) | 556,823 (5%) | |
| Not Hispanic or Latino | 120,343 (87%) | 72,036 (87%) | 8,347,958 (78%) | |
| Unknown | 13,122 (9%) | 6,977 (8%) | 1,782,928 (17%) | |
| Rural, n (%) | 55,598 (43%) | 32,252 (42%) | 3,463,456 (34%) | |
| Region, n (%) | ||||
| West | 27,900 (20%) | 15,074 (18%) | 2,369,694 (22%) | |
| Midwest | 36,531 (26%) | 19,131 (23%) | 2,439,238 (23%) | |
| South | 54,512 (39%) | 30,576 (37%) | 4,032,728 (38%) | |
| Northeast | 20,096 (14%) | 17,776 (22%) | 1,840,928 (17%) | |
| Surgical or Transbronchial Lung Biopsy | 3,029 (2%) | 2,895 (4%) | 14,502 (0.1%) | |
| Tobacco Use | 109,895 (79%) | 69,144 (84%) | 5,543,334 (52%) | |
Definition of abbreviations: IPF = idiopathic pulmonary fibrosis; SD = standard deviation.
*
Control population defined as Veterans with no IPF diagnosis codes. All P values less than 0.001 comparing broad case definition to control population. P values were calculated with t test for continuous variables and chi-square test for categorical variables.