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. 2022 Feb 1;19(2):196–203. doi: 10.1513/AnnalsATS.202103-295OC

Table 2.

Risk factors associated with incident idiopathic pulmonary fibrosis among male Veterans

  Broad Case Definition
IPF: n = 129,598
Non-IPF: n = 9,767,864
Narrow Case Definition
IPF: n = 76,779
Non-IPF: n = 9,767,864
Odds Ratio
(95% CI)
P Value Odds Ratio
(95% CI)
P Value
Age        
 ⩽60 yr (Reference)   (Reference)  
 >60–70 yr 2.83 (2.78–2.89) <0.001 3.11 (3.04–3.19) <0.001
 >70–80 yr 4.39 (4.30–4.47) <0.001 4.77 (4.65–4.89) <0.001
 >80 yr 3.21 (3.15–3.28) <0.001 2.86 (2.78–2.94) <0.001
Race        
 White (Reference)   (Reference)  
 Black or African American 0.90 (0.88–0.91) <0.001 0.93 (0.90–0.95) <0.001
 Asian/Native Hawaiian or Pacific Islander/American Indian 0.86 (0.82–0.90) <0.001 0.86 (0.81–0.91) <0.001
Ethnicity        
 Hispanic or Latino (Reference)   (Reference)  
 Not Hispanic or Latino 0.99 (0.96–1.02) 0.44 0.94 (0.90–0.97) 0.001
Tobacco Use 2.94 (2.89–2.98) <0.001 4.02 (3.93–4.11) <0.001
Rural Residence 1.26 (1.25–1.28) <0.001 1.21 (1.19–1.23) <0.001

Definition of abbreviations: CI = confidence interval; IPF = idiopathic pulmonary fibrosis.