Table 2.
Psychotropic medication. ATC code, class | Model 1 | Model 2 | Model 3 | Model 4 | ||||||||
OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | |
Any psychotropic medication | 1.12 | 1.10 to 1.13 | <0.0001 | 1.15 | 1.13 to 1.16 | <0.0001 | 1.16 | 1.14 to 1.17 | <0.0001 | 1.15 | 1.13 to 1.17 | <0.0001 |
N05A, antipsychotics | 0.95 | 0.93 to 0.98 | 0.00019 | 1.02 | 0.99 to 1.05 | 0.212 | 1.10 | 1.07 to 1.13 | <0.0001 | 1.09 | 1.06 to 1.12 | <0.0001 |
N05B, anxiolytics | 1.10 | 1.07 to 1.12 | <0.0001 | 1.14 | 1.12 to 1.17 | <0.0001 | 1.16 | 1.14 to 1.19 | <0.0001 | 1.16 | 1.14 to 1.19 | <0.0001 |
N05C, hypnotics/sedatives | 1.17 | 1.14 to 1.20 | <0.0001 | 1.19 | 1.16 to 1.21 | <0.0001 | 1.18 | 1.15 to 1.20 | <0.0001 | 1.17 | 1.14 to 1.20 | <0.0001 |
N06A, antidepressants | 1.11 | 1.09 to 1.13 | <0.0001 | 1.14 | 1.12 to 1.15 | <0.0001 | 1.16 | 1.14 to 1.17 | <0.0001 | 1.15 | 1.13 to 1.16 | <0.0001 |
N06B, psychostimulants | 0.98 | 0.92 to 1.05 | 0.56 | 1.05 | 0.98 to 1.13 | 0.142 | 1.08 | 1.00 to 1.15 | 0.039 | 1.07 | 1.00 to 1.15 | 0.057 |
N06C, psycholeptics and psychoanaleptics | 1.30 | 1.20 to 1.42 | <0.0001 | 1.31 | 1.20 to 1.42 | <0.0001 | 1.27 | 1.17 to 1.39 | <0.0001 | 1.26 | 1.16 to 1.38 | <0.0001 |
Model 1 is the unadjusted model; Model 2 is Model 1 adjusted for age group, education and marital status; Model 3 is Model 2 adjusted for socioeconomic status and income level; Model 4 is Model 3 adjusted for recent pregnancy (in 2017), abortion (in 2016–2017) and sterilisation (before 2017).
ATC, Anatomical Therapeutic Chemical; HC, hormonal contraception.