Table 2.

First-line treatment and efficacy.

First line therapy after transformation	Cases	Median PFS (range)	Ratio of effective cases (ORR)
Chemo+radi+targeted	2	11.5 m (9–12 m)	50%
Chemo+radiation	4	6.5 m (6–7 m)	33%
Chemo+targeted	9	6 m (0.5–8 m)	33%
Chemotherapy	42	4 m (0.5–24 m)	53%
Targeted	3	3.5 m (2–5 m)	50%
None	4	–	–
Total	64	4.0 m (95% CI, 3.16–7.50 m)	48%

Chemo, Chemotherapy; Radi, Radiation; m, months; PFS, Progression-free survival; ORR, Objective response rate.