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. 2022 Feb 23;17:82. doi: 10.1186/s13023-022-02245-5

Table 1.

Characteristics of Wilson disease patients

Sex Age at diagnosis (years old) Familiar history Predominant features Neurologic symptoms Kayser–Fleischer rings Staging of liver fibrosis (Metavir score) Hepatic liver failure Treatment Liver transplant Outcome Follow-up (years)
1 Male 18 No Hepatic No No F4 No Penicillamine No Alive 29
2 Male 22 No Neuropsychiatric Yes Yes F3 No Penicillamine >> Trientin No Alive 4
3 Male 43 No Hepatic No No F4 No Trientin No Alive 4
4 Female 15 No Hepatic No No F1 No Zinc No Alive 25
5 Female 12 No Hepatic No No F2 No Penicillamine No Alive 8
6 Male 30 No Hepatic No Yes F4 No Penicillamine Yes Alive 20
7 Female 8 No Hepatic No No F2 No Trientin No Alive 14
8 Female 13 Yes Neuropsychiatric Yes Yes F4 Yes Yes Alive 15
9 Female 16 No Hepatic No No F4 No Yes Alive 29
10 Male 22 Yes Hepatic No Yes F4 No Yes Alive 14
11 Male 18 No Ophthalmologic No Yes F1 No Penicillamine No Alive 32
12 Male 25 No Neuropsychiatric Yes Yes F4 No Yes Alive 20
13 Female 25 No Neuropsychiatric Yes Yes F4 No Penicillamine No Death 12
14 Male 8 No Hepatic No No F1 No Trientin No Alive 18
15 Male 18 Yes Hepatic No No F4 No Penicillamine >> Trientin No Alive 17
16 Male 9 Yes Hepatic No Yes F4 No Penicillamine No Alive 18
17 Male 22 No Hepatic No Yes F4 Yes Yes Alive 22
18 Female 50 No Hepatic No No F2 No Penicillamine >> Trientin No Alive 15
19 Female 18 No Hepatic No Yes F4 Yes Yes Alive 22
20 Male 25 No Neuropsychiatric Yes Yes F4 No Yes Death 7
21 Female 16 No Neuropsychiatric Yes Yes F4 No Penicillamine Yes Alive 19
22 Female 19 No Hepatic Yes Yes F4 Yes Yes Alive 16
23 Male 21 Yes Hepatic Yes No F2 No Trientin No Alive 20
24 Female 32 No Hepatic No No F2 No Penicillamine >> Trientin No Alive 20