Fig. 6.

Copy number alterations in the high-risk and low-risk groups. A Copy number profiles of the high-risk (above) and low-risk (below) groups, with gains shown in red and losses shown in blue. B Detailed cytobands with focal amplification (left) and deletion (right) peaks identified in the high-risk group. C Detailed cytobands with focal amplification (left) and deletion (right) peaks identified in the low-risk group. D Venn diagrams showing significantly amplified genes in the high-risk and low-risk groups. Each circle in the Venn diagram represents one group, and the number in the overlaid area represents common genes between the groups. E Cluster analysis of the top 10 biological processes in the high-risk (left) and low-risk (right) groups. F Circular plot of the top 10 biological processes and corresponding enriched genes in the high-risk (left) and low-risk (right) groups. G Comparison of the mRNA expression of PD-L1 and PD-L1 between the high-risk and low-risk groups in the cohort from TCGA