Figure 1.

Cytotoxicity of the WPE, RPE, CE, and CoE was evaluated using Alamar Blue assay on the cancerous cell lines MDA-kb2 (A), A549 (B), and T47D-KBluc (C) and normal human gingival fibroblasts (D) after a 24 h exposure. The results are presented as the means ± standard deviations of three biological replicates, each one including 6 technical replicates. The values were expressed as relative values compared to the negative control (DMSO 0.2%) (100%). Asterisks (*) indicate statistically significant differences in comparison with negative control (ANOVA + Holm–Sidak post hoc test at p < 0.05).