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. 2022 Jan 19;11(2):130. doi: 10.3390/antibiotics11020130

Table 2.

The frequency of association between different β-lactamase classes and resistance to ceftazidime–avibactam and ceftolozane–tazobactam among 75 MDR-P. aeruginosa isolates collected from Hamad Medical Corporation between 2014–2017.

Antibiotic β-Lactamase Class Resistant Susceptible p-Value *
N = 37 N = 38
Ceftazidime–avibactam Class A 48.6% 31.6% 0.131
Class B 54.1% 0% <0.001
Class C 100% 92.1% 0.240
Class D 91.9% 100% 0.115
Ceftolozane–tazobactam N = 40 N = 35
Class A 55% 22.9% 0.005
Class B 50% 0% <0.001
Class C 95% 97.1% 0.99
Class D 92.5% 100% 0.243

p-value was calculated using Pearson Chi-Square test,  p-value was calculated using Fisher Exact test.