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. 2022 Jan 31;11(2):288. doi: 10.3390/antiox11020288

Figure 6.

Figure 6

Effect of decreased NKA α2 expression in the PVN on the expression of TLR4, MyD88, NF-κB p65, and TNF-α in rats with salt-induced hypertension. (A) A representative immunoblot densitometric analysis of protein expression of TLR4, MyD88, NF-κB p65, and TNF-α in the PVN in different groups. (B–E) Column diagram showing the effects of microinjections NKA α2 shRNA in the PVN on the protein expression of TLR4, MyD88, NF-κB p65, and TNF-α. (F,G) Immunohistochemistry and column diagram showing the effects of NKA α2 shRNA microinjections on the number of Caspase-3 positive neurons in the PVN in different groups. * p < 0.05 versus the normal salt groups (the normal salt + NKA α2 shRNA or normal salt + scrambled shRNA group); # p < 0.05, the high salt + NKA α2 shRNA group versus the high salt + scrambled shRNA group. Values are expressed as the mean ± SEM (n = 6).