Figure 2.

Inhibitory effects of CA extract in a mouse model of oxazolone-induced atopic dermatitis (AD). (A) Schematic representation of the experiment. (B) Two groups of female ICR mice (n = 3 per group) were treated with oxazolone together with either vehicle (DMSO) or CA extract. Imaging analysis was performed on days 7 and 15. The extent of ear edema was assessed by measuring ear thickness at the indicated intervals using a micrometer. Data represent the mean ± SD (n = 5). (C) mRNA levels of IL-6, TNF-α, and β-actin of ear tissues were measured using RT-PCR and then quantified. * p < 0.05, ** p < 0.01 compared with oxazolone-treated group.