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. 2022 Jan 19;11(2):191. doi: 10.3390/antiox11020191

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of Pioglitazone (20 mg/kg/day) on gentamycin induced testicular damage in group (GV, PIO20) (a) 100×, (b) 200×, and (c) 400×. There is marked improvement of pathological changes, tubules are regularly arranged with regular contours, regular germ cell lining with regular maturation till spermatozoa stage (red arrow). There is focal minimal vacuolar degeneration of few cells (green arrow). There is mild focal interstitial edema (blue arrow) and mildly thickened tunica (black arrow).