Table 1.
Important regulatory factors in pathogenesis of ALS.
| Gene | Degree | Outdegree | p-Value | FDR | Fold Change |
|---|---|---|---|---|---|
| CEBPD | 28 | 25 | 1.02 × 10−6 | 1.05 × 10−4 | 3.9261 |
| STAT6 | 41 | 38 | 1.37 × 10−5 | 0.001371759 | 3.7290 |
| RUNX1 | 63 | 58 | 3.24 × 10−14 | 3.57 × 10−12 | 3.3537 |
| GABPB2 | 51 | 50 | 7.13 × 10−5 | 0.006990821 | 3.1583 |
| CEBPB | 70 | 67 | 0 | 0 | 2.9424 |
| FOXO1 | 40 | 39 | 5.90 × 10−8 | 6.20 × 10−6 | 2.6586 |
| PAX6 | 20 | 14 | 7.42 × 10−6 | 7.49 × 10−4 | 2.5465 |
| REL | 23 | 22 | 4.63 × 10−5 | 0.00458507 | 2.4250 |
| STAT5A | 87 | 85 | 0 | 0 | 2.2199 |
| FOXJ1 | 44 | 44 | 6.03 × 10−9 | 6.39 × 10−7 | 2.1753 |
| SMAD3 | 26 | 25 | 6.15 × 10−6 | 6.28 × 10−4 | 2.0401 |
| NOG | 53 | 53 | 1.30 × 10−7 | 2.34 × 10−6 | 0.4031 |
Legend: FDR, false discovery rate.