Table 2.
Isolates (n) | Wards | Antimicrobial Agents | Antimicrobials Susceptibility (%) by Year | Correlation | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | r | p | |||
Blood (154) |
All wards (154) |
Imipenem/cilastatin | 42.86 | 36.36 | 50.00 | 57.89 | 32.00 | 33.33 | 34.38 | −0.39 | 0.387 |
Meropenem | 42.86 | 36.36 | 52.38 | 57.89 | 32.00 | 33.33 | 30.00 | −0.46 | 0.294 | ||
MDR-AB | 57.14 | 61.54 | 42.31 | 42.86 | 72.00 | 72.73 | 63.64 | 0.44 | 0.318 | ||
Non-ICU wards (84) |
Imipenem/cilastatin | 28.57 | 60.00 | 50.00 | 84.62 | 35.29 | 50.00 | 50.00 | 0.13 | 0.788 | |
Meropenem | 28.57 | 60.00 | 54.55 | 84.62 | 35.29 | 50.00 | 47.06 | 0.07 | 0.884 | ||
MDR-AB | 71.43 | 50.00 | 42.86 | 23.08 | 70.59 | 60.00 | 52.94 | −0.04 | 0.940 | ||
ICU wards (70) |
Imipenem/cilastatin | 57.14 | 16.67 | 50.00 | 0.00 | 25.00 | 16.67 | 14.29 | −0.58 | 0.175 | |
Meropenem | 57.14 | 16.67 | 50.00 | 0.00 | 25.00 | 16.67 | 7.69 | −0.63 | 0.131 | ||
MDR-AB | 42.86 | 71.43 | 41.67 | 75.00 | 75.00 | 83.33 | 75.00 | 0.33 | 0.465 | ||
Sputum and BAL (1198) |
All wards (1198) |
Imipenem/cilastatin | 25.25 | 20.00 | 18.40 | 19.55 | 19.31 | 20.43 | 14.90 | −0.74 | 0.059 |
Meropenem | 24.49 | 20.69 | 18.01 | 19.55 | 17.59 | 19.46 | 13.56 | −0.83 * | 0.021 | ||
MDR-AB | 49.36 | 78.23 | 83.95 | 81.54 | 39.59 | 75.51 | 84.76 | 0.07 | 0.879 | ||
Non-ICU wards (694) |
Imipenem/cilastatin | 24.53 | 22.22 | 23.30 | 21.62 | 20.61 | 19.19 | 15.18 | −0.92 ** | 0.003 | |
Meropenem | 25.00 | 23.33 | 22.33 | 21.62 | 18.60 | 18.18 | 13.68 | −0.97 ** | 0.000 | ||
MDR-AB | 46.07 | 75.82 | 80.39 | 81.69 | 83.33 | 76.19 | 86.36 | 0.07 | 0.879 | ||
ICU wards (504) |
Imipenem/cilastatin | 26.09 | 16.36 | 10.00 | 16.95 | 16.90 | 21.84 | 14.58 | −0.25 | 0.589 | |
Meropenem | 23.91 | 16.36 | 10.34 | 16.95 | 15.71 | 20.93 | 13.41 | −0.29 | 0.528 | ||
MDR-AB | 53.73 | 82.14 | 90.00 | 81.36 | 84.51 | 74.73 | 83.00 | −0.25 | 0.589 |
* Correlation is significant at the 0.05 level (2-tailed); ** Correlation is significant at the 0.01 level (2-tailed).