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. 2022 Jan 27;11(2):163. doi: 10.3390/antibiotics11020163

Table 2.

Companies involved in the development of phage-based products to control or prevent bacterial infections in aquaculture.

Company Country Target Application References
Intralytix Inc. Baltimore, MD, USA Phage-based application to fight V. coralliilyticus and V. tubiashii infections in hatchery-raised oysters [203]
BASF New Business GmbH Ludwigshafen, Germany Products that mix phages covalently to particles into the feed to treat infections caused by Vibrio, Yersinia, Aeromonas, Rickettsia, Moritella, Lactococcus, Piscirickettsia, Flavobacterium, Pseudomonas, or Photobacterium [204]
Proteon Pharmaceuticals S.A. Łódz, Poland Natural feed additive called BAFADOR® that can control bacterial infections caused by Pseudomonas spp and Aeromonas spp. serotypes in commercial aquaculture [50]
Fixed Phage Ltd. Glasgow, Scotland Phage particles immobilized in pellets that can be added to fish and crustacean feed to treat bacterial infections in aquaculture, including Early Mortality Syndrome in shrimps and Flavobacteria infections in salmonids [204]
ACD Pharma Oslo, Norway Phage-based solutions against several aquaculture pathogens; CUSTUS® YRS is a product that reduces the infective pressure from Y. ruckeri in aquaculture water [205]
Mangalore Biotech Laboratory Karnataka, India A product called LUMI-NIL MBL prevents and treats Vibrio harveyi-caused luminous vibriosis [206]
Phage Biotech Ltd. Rehovot, Israel Phage treatment for V. harveyi in aquaculture shrimps [202]
Biologix Australia Phage treatment for Vibrio sp. associated with mortalities in aquaculture [207]
Aquatic Biologicals Greece Phage treatment against several pathogens associated with mortalities in aquaculture [208]