Table 2.
Compounds identified in the Olea europaea leaf extract.
| Compound | Formula | (M–H)− | RT, min | Refs. | Quantity Mean ± SD, μg/g DW |
|---|---|---|---|---|---|
| Hydroxytyrosol b,c | C8H10O3 | 153.0557 | 7.12 | [27,58] | 1695 ± 11 d |
| Hydroxytyrosol glucoside b,c | C14H20O8 | 315.1085 | 7.78 | [59] | 203 ± 8 d |
| Oleoside b,c | C16H22O11 | 389.1089 | 7.94 | [60] | 44 ± 6 k |
| 4-Hydroxybenzoic acid a | C7H6O3 | 137.0244 | 8.35 | [61] | 41 ± 3 |
| Aesculin b,c | C15H16O9 | 339.0722 | 8.59 | [60] | 21.8 ± 0.9 d |
| Chlorogenic acid a | C16H18O9 | 353.0878 | 9.01 | [59] | 17 ± 2 |
| NI c | – | 377.1487 | 9.39 | – | NQ |
| Luteolin rutinoside b,c | C27H30O16 | 609.1461 | 9.61 | [62] | 5.7 ± 0.5 j |
| C10 isoprenoidc | C17H24O11 | 403.1246 | 9.67 | [63] | NQ |
| NI c | – | 305.0739 | 9.95 | NQ | |
| Demethyloleuropein b,c | C24H30O13 | 525.1614 | 10.05 | [63] | 4.0 ± 0.2 k |
| Hydroxyphenylacetic acid b,c | C8H8O3 | 151.0401 | 10.09 | [64] | 0.858 ± 0.004 d |
| Rutin a | C27H30O16 | 609.1461 | 10.18 | [21,27,58] | 7.5 ± 0.2 |
| Verbascoside b,c | C29H36O15 | 623.1981 | 10.22 | [21,27] | 120.4 ± 0.6 e |
| p-Coumaric acid a | C9H8O3 | 163.0401 | 10.26 | [58,61] | 1.80 ± 0.04 |
| Luteolin O-glucoside b,c | C21H20O11 | 447.0933 | 10.41 | [27,58,60] | 31.0 ± 0.6 j |
| Isoverbascoside b,c | C29H36O15 | 623.1981 | 10.49 | [27] | 18.8 ± 1.3 e |
| Ferulic acid a | C10H10O4 | 193.0506 | 10.60 | [58,61] | 1.6 ± 0.2 |
| Apigenin 7-O-glucoside b,c | C21H20O10 | 431.0984 | 10.88 | [21,27] | 4.6 ± 0.4 j |
| Luteolin O-glucoside b,c | C21H20O11 | 447.0933 | 10.93 | [21,27,60] | 17.3 ± 1.1 j |
| Elenolic acid b,c | C11H14O6 | 241.0718 | 11.03 | [59] | 7.2 ± 0.4 k |
| Oleuropein a | C25H32O13 | 539.1770 | 11.10 | [27,58,59,60] | 8681 ± 85 |
| NI c | – | 601.2146 | 11.61 | – | NQ |
| Elenolic acid derivative b,c | – | 241.0718 | 12.16 | – | 2.5 ± 0.3 k |
| Luteolin b,c | C15H10O6 | 285.0405 | 12.20 | [58,60] | 18 ± 2 j |
| Quercetin b,c | C15H10O7 | 301.0354 | 12.22 | [58] | 21 ± 2 j |
| NI c | – | 377.1253 | 12.47 | – | NQ |
| Apigenin derivative b,c | – | 269.0455 | 12.96 | – | 1.1 ± 0.2j |
| NI c | – | 377.1255 | 13.23 | – | 208 ± 12 d |
| NI c | – | 377.1255 | 13.45 | – | 53 ± 7 d |
| Chrysoeriol b,c | C16H12O6 | 299.0561 | 14.89 | [65] | 4.5 ± 0.2 j |
| NI c | – | 545.1911 | 14.94 | – | NQ |
| NI c | – | 721.3611 | 15.80 | – | NQ |
| Apigenin derivative b,c | – | 269.0455 | 16.02 | – | 1.8 ± 0.3 j |
| C30 isoprenoid c | C30H48O4 | 471.3480 | 17.64 | [63] | NQ |
| NI c | – | 401.3017 | 20.46 | – | NQ |
| NI c | – | 401.3014 | 20.99 | – | NQ |
NI—not identified; NQ—not quantified; a confirmed by standard; b confirmed by reference; c confirmed by HRMS; d expressed as p-coumaric acid; e expressed as caffeic acid; j expressed as rutin; k expressed as oleuropein.