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Effect of mitoTEMPO (mT) on generation of ROS in different body compartments of rats. (a) Rats were challenged with 2.5 mg/kg body weight lipopolysaccharide (LPS) and biological fluids were withdrawn after 16 h. (b) Scheme of H2O2 production rate assessed by Amplex Red by calculating the slope. (c–e) Effect of mitoTEMPO on H2O2 production rate of white blood cells (c), peritoneal lavage (d), and bronchoalveolar lavage (e). Unpaired t-test, * p < 0.05, ** p < 0.01.
