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. 2022 Jan 23;11(2):215. doi: 10.3390/antiox11020215

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Total ion chromatogram (TIC) of Centella asiatica water extract product (CAP) showing peaks corresponding to the triterpene and caffeoylquinic acid components of interest. The total ion chromatogram in negative ion mode corresponds to 2 g (blue) and 4 g (pink) of the Centella asiatica water extract present in each sachet (~20 g). The major compounds are indicated in the chromatogram. Extracted ion chromatograms (XIC) are shown for the monocaffeoylquinic acids (mono-CQAs; m/z 353.08, [M-H]⁻), the dicaffeoylquinic acids (Di-CQA, m/z 515.12, [M-H]⁻), madecassic acid (m/z 503.3, [M-H]⁻), and asiatic acid (m/z 487.3, [M-H]⁻).