Table 2.
Antibiotic resistance of 20 different types of antibiotics and its statistical significance, comparing revision TKA and revision THA.
| Type of Antibiotic | TKA (n = 99) | THA (n = 129) | p-Value (Significant < 0.05) | ||
|---|---|---|---|---|---|
| S | R | S | R | ||
| Penicillin grp. | |||||
| Ampicillin | 14/30 (46.7%) | 16/30 (53.3%) | 14/35 (40.0%) | 21/35 (60.0%) | 0.751 |
| Oxacillin | 49/74 (66.2%) | 25/74 (33.8%) | 39/80 (48.8%) | 41/80 (51.3%) | 0.03 |
| Penicillin | 35/89 (39.3%) | 54/89 (60.7%) | 29/91 (31.9%) | 62/91 (68.1%) | 0.3 |
| Cephalosporins | |||||
| Cefazolin | 14/21 (66.7%) | 7/21 (33.3%) | 11/17 (64.7%) | 6/17 (35.3%) | 0.270 |
| Cefuroxime | 20/27 (74.1%) | 7/27 (25.9%) | 12/20 (60.0%) | 8/20 (40.0%) | 0.055 |
| Fluoroquinolones | |||||
| Ciprofloxacin | 62/82 (75.6%) | 20/82 (24.4%) | 52/105 (49.5%) | 53/105 (50.5%) | <0.001 |
| Levofloxacin | 24/31 (77.4%) | 7/31 (22.6%) | 24/63 (38.1%) | 39/63 (61.9%) | <0.001 |
| Moxifloxacin | 66/85 (77.7%) | 19/85 (22.3%) | 58/101 (57.4%) | 43/101 (42.6%) | 0.005 |
| Lincosamide | |||||
| Clindamycin | 60/90 (66.7%) | 30/90 (33.3%) | 47/89 (52.8%) | 42/89 (47.2%) | <0.001 |
| Sulfonamide | |||||
| Co-trimoxazole | 32/40 (80.0%) | 8/40 (20.0%) | 59/90 (65.6%) | 31/90 (34.4%) | <0.001 |
| Macrolide | |||||
| Erythromycin | 36/62 (58.1%) | 26/62 (41.9%) | 36/77 (46.8%) | 41/77 (53.2%) | 0.373 |
| Phosphonic acid | |||||
| Fosfomycin | 56/76 (73.7%) | 20/76 (26.3%) | 56/92 (60.9%) | 36/92 (39.1%) | 0.138 |
| Fusidane class | |||||
| Fusidic acid | 57/74 (77.0%) | 17/74 (23.0%) | 60/80 (75.0%) | 20/80 (25.0%) | 0.121 |
| Carbapenem | |||||
| Imipenem | 15/15 (100.0%) | 0/15 (0.0%) | 38/41 (92.7%) | 3/41 (7.3%) | 0.010 |
| Oxazolidinone | |||||
| Linezolid | 63/63 (100.0%) | 0/63 (0.0%) | 88/89 (98.9%) | 1/89 (1.1%) | 0.490 |
| Antimycobacterial | |||||
| Rifampicin | 49/50 (98.0%) | 1/50 (2.0%) | 56/72 (77.8%) | 16/72 (22.2%) | 0.005 |
| Tetracycline grp. | |||||
| Tetracycline | 35/36 (97.2%) | 1/36 (2.8%) | 64/72 (88.9%) | 8/72 (11.1%) | 0.009 |
| Tigecycline | 61/62 (98.4%) | 1/62 (1.6%) | 102/102 (100.0%) | 0/102 (0.0%) | 0.015 |
| Glycopeptides | |||||
| Teicoplanin | 60/60 (100.0%) | 0/60 (0.0%) | 82/83 (98.8%) | 1/83 (1.2%) | 0.590 |
| Vancomycin | 72/72 (100.0%) | 0/72 (0.0%) | 85/86 (98.8%) | 1/86 (1.2%) | 0.403 |
TKA, total knee arthroplasty; THA, total hip arthroplasty; n, number; S, sensitive; R, resistant; grp., group.