Figure 6.

Effects of Na₂SeO₃ and L-SeMC on oxidative stress in H₂O₂-induced AML-12 cells. (A) Cell viability of AML-12 cells was measured by CCK-8 after co-treatment with 100 μM H₂O₂ and different concentrations of Na₂SeO₃ (0–1000 nM) for 3 h (n = 7, *** p < 0.001, ** p < 0.01, * p < 0.05 vs. H₂O₂ group). (B) Cell viability of AML-12 cells was measured by CCK-8 after co-treatment with 100 μM H₂O₂ and different concentrations of L-SeMC (0–45 μM) for 3 h (n = 7, *** p < 0.001, ** p < 0.01, * p < 0.05 vs. H₂O₂ group). (C) The protein level of SEPP1, NRF2, and NQO1 (n = 7, ** p < 0.01, * p < 0.05).