Table 1.
Basic information and susceptibility profiles of K. pneumoniae harbouring tmexCD1-toprJ1 or tet(A) mutation.
| Strain | Resistance Gene | Sources | MIC (;µg/mL) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GEN | CFF | CIP | ENR | TET | TGC | DOX | MET | MER | CL | KAN | |||
| RGT9-1 | tmexCD1-toprJ1,oqxAB, QnrB4, QnrS1, aac(3)-IId, aac(6’)Ib-cr, aadA16, aadA2 | Swine Faeces | 128 | 8 | 8 | 8 | >128 | 64 | 64 | 50 mg | ≤0.25 | ≤0.25 | >256 |
| RGF15-2-1 | tmexCD1-toprJ1,oqxAB, QnrB4, QnrS1, aac(3)-IId, aac(6’)Ib-cr, aadA16, aadA2 | Swine Faeces | 128 | 16 | 8 | 8 | >128 | 64 | 64 | 50 mg | ≤0.25 | ≤0.25 | >256 |
| RGF-131 | tet(A), QnrS1, aac(3)-IId, aac(6’)Ib-cr, aadA16, aadA1, blaCTX-M-55, blaSHV-11, blaSHV-1 | Swine Faeces | 64 | 4 | 4 | 4 | >128 | 32 | 64 | 50 mg | ≤0.25 | ≤0.25 | >256 |
GEN, gentamicin; CFF, ceftiofur; CIP, ciprofloxacin; ENR, enrofloxacin; TET, tetracycline; TGC, tigecycline; DOX, doxycycline; MET, metformin; MER, meropenem; CL, colistin; and KAN, kanamycin.