Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
GPR81 modulates mitochondrial metabolism gene expression. Evaluation of relative mRNA expression levels of (A) PGC1alpha, (B) SIRT1, (C) COX IV, (D) COX II, (E) ATPsyn, (F) MCT1, following 24 h of lactate (20 mM), 3,5-DHBA (150 μM) and 3-OBA (3 mM) exposition, analyzed by real-time PCR. The calculated value of 2−ΔΔCt in untreated controls is 1. Data are expressed as mean ± SD of at least four independent experiments. * p < 0.05; ** p < 0.005; *** p < 0.001; **** p < 0.0001.
