Table 2.

List of recently published outstanding reviews on composition and health benefits of citrus bioactive compounds.

Compounds	Review Highlights	Reference
Essential oil	Extraction, purification, detection methods, composition, and applications of citrus essential oil	[10]
	Composition of volatile compounds from peel, leaves, and flowers of different citrus species	[11]
Flavanones (hesperidin and naringin)	The intestinal fate, bioavailability, intestinal metabolism, and interaction with the gut microbiota	[12]
Flavones	Sources, antioxidant, anti-inflammatory, antimicrobial, anticancer properties	[13]
Flavonoids	Chemistry, biosynthesis, composition, extraction techniques, health benefits, and industrial applications	[14]
	Composition, antioxidant evaluation, and regulation of Nrf2-Keap1 pathway by citrus flavonoids	[15]
	Role of citrus flavonoids in brain health: evidence from preclinical and human studies	[16]
	Biosynthesis, location, and distribution of flavonoids in citrus plants, factors affecting biosynthesis, and health-promoting properties	[17]
	In vitro, in vivo, and human studies of citrus flavonoids in minimizing the incidence of inflammatory bowel disease	[18]
	Antidiabetic potential of 19 citrus flavonoids, including diosmin, hesperidin, hesperetin, naringin, naringenin, nobiletin, neohesperidin, quercetin, rutin, and tangeretin	[19]
	Therapeutic potential in diabetes and diabetic cardiomyopathy, endothelial dysfunction, atherosclerosis, and platelet function	[20]
	Chemistry, metabolism, bioavailability, biotransformation and delivery systems, and health benefits	[6]
Hesperidin and vitamin C	Antiviral properties against acute respiratory syndrome coronavirus 2 (SARS-CoV-2)	[21]
Naringenin	Antidiabetic properties; in vitro, in vivo, and human studies	[22]
	Combating oxidative stress disorders: cardiovascular disease, diabetes mellitus, neurodegenerative disease, pulmonary disease, cancer, and nephropathy	[23]
Nobiletin	Beneficial effects against Alzheimer’s disease (AD) and Parkinson’s disease (PD)	[24]
Nobiletin, 5-demethylnobiletin, and derivatives	Beneficial effects against colon cancer, pharmacokinetics, and bioavailability	[25]
Nutrients and bioactive	Description of the genus Citrus, the composition of nutrients and bioactive components, and biological activities of lemon extract and essential oil	[26]
	Nutrients (proteins, lipids, vitamins, minerals, fiber) and bioactive (flavonoids, essential oil, limonoids, carotenoids, synephrine) content, their structural characteristics, and health benefits	[5]
Polymethoxyflavones (PMF)	Biological properties against metabolic disorder, atherosclerosis, inflammation, neuroinflammation, cancer, and oxidation	[27]