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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Pediatr Hematol Oncol. 2021 Apr 1;38(5):420–433. doi: 10.1080/08880018.2020.1856986

Table 5.

Factors associated with difficult lumbar punctures and procedural details.

Factors associated with difficult lumbar puncture
Patients
Procedures
Factor Findings n=33 (%) n=64 (%)
BMIa BMI < 25 (normal) 8 (24.2) 19 (29.7)
BMI ≥ 25 (overweight/obese) 27 (81.8) 45 (70.3)
Anatomic abnormalities of the lumbar spine Known abnormalities 17 (51.5) 39 (60.9)
 Spinal stenosis 12 (36.4) 35 (54.7)
 Arachnoiditis 4 (12.1) 9 (14.1)
 Postsurgical changes 2 (6.1) 2 (3.1)
 Scoliosis 2 (6.1) 2 (3.1)
 Otherb 4 (12.1) 9 (14.1)
No known abnormalities 16 (48.5) 25 (39.1)
History of previous LPsa ≥ 5 previous LPs 11 (33.3) 25 (39.1)
< 5 previous LPs 14 (42.4) 32 (50)
Unknown 8 (24.3) 7 (10.9)
Age <12 months Age < 12 months 3 (9.1) 4 (6.25)
Age > 12 months 30 (90.9) 60 (93.8)
History of back surgery History of back surgery 3 (9.1) 3 (4.7)
No history of back surgery 30 (90.9) 61 (95.3)
Procedural details
Patients
Procedures
Category Details N=33 (%) n=64 (%)

Mode of imaging Fluoroscopy 31 (93.9) 60 (93.8)
Ultrasound 2 (6.1) 4 (6.3)
LP procedure success rate Successful 29 (87.9) 59 (92.2)
Unsuccessful 5 (15.2) 5 (7.8)
At least one complication 24 (72.7) 37 (57.8)
LP procedure complication details Bloody CSFc 19 (57.6) 27 (42.1)
Multiple attempts 11 (33.3) 16 (25)
Multiple levels 4 (12.1) 4 (6.25)
Postprocedure headache 2 (6.1) 2 (3.1)

Abbreviations: BMI, body mass index; CSF, cerebrospinal fluid; LP, lumbar puncture.

a

As recorded at the time of procedure; two patients had BMIs that varied between < 25 to > 25 among multiple procedures, and four patients had multiple procedures that varied between < 5 or ≥ 5 previous LPs.

b

Epidural hematoma (n = 1), reversal of lumbar lordosis (n = 1), and subdural fluid collection/CSF leak (n = 2).

c

Bloody CSF was defined as > 10 red blood cells per mm3 of CSF.