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. 2022 Feb 10;10:813314. doi: 10.3389/fcell.2022.813314

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Copyright © 2022 Demirci, Heger, Katkat, Papatheodorou, Brazma and Ozhan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Network analysis of zebrafish brain regeneration at three stages reveals stage-specific modules. (A) Heatmap representing relative expression (z-score) of genes that are enriched in each module for the three stages of the adult zebrafish brain regeneration. Each row represents a sample, and each column shows a single gene. Red and green shades show high or low relative expressions, respectively. (B) DAVID was used to show the most significantly enriched GO-BP terms based on the transcriptional changes of each significant module and their associated enrichment p-values for Top 10 GO-BP terms. The heatmap scale shows log₁₀ of the ease p-values for the most significantly enriched GO terms. dpl: days post-lesion, ctrl: control.