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Role of miRNA223 in different cancers: (A) activated miR-223 negatively regulates the TLR4/MyD88-NF-κB signaling pathway. (B) miR-223 plays a role as a tumor suppressor in hepatocellular carcinoma by apoptosis through mTOR pathway activation. (C) miR-223 inhibits NLRP3 and its downstream factor CARD-PYD in breast cancer. (D) In colon cancer, miR-223 downregulates the transcription factor FoxO3a and BAM.
