Table 2.
Effects of ALA-PDT on exosomes 1.
| Surface Marker | PDT Effect (Avg.) | Cell Type | Possible Biological Function |
|---|---|---|---|
| CD29 | 9.4 | White blood cells | Cell adhesion |
| CD9 | 8.8 | Lymphocyte, macrophage | Platelet activation and aggregation and cell adhesion and migration |
| CD40 | 7.8 | B-cell, macrophage | Cell proliferation and signal transduction |
| CD31 | 7.6 | White blood cells | Cell adhesion, activation, and migration |
| HLA-ABC | 7.5 | Nucleated cells | MHC class I molecules presented to CD8+ T cells |
| CD41b | 7.4 | Stem cell, platelet | Cell adhesion and platelet aggregation |
| CD69 | 7.4 | White blood cells | Lymphocyte activation and proliferation |
| HLA-DRDPDQ | 7.1 | Antigen-presenting cell | MHC class II molecules presented to CD4+ T cells |
| CD44 | 7.1 | White blood cells | Cell adhesion |
| CD81 | 6.5 | White blood cells but granulocyte | Cell adhesion |
| SSEA-4 | 6.5 | Embryonic stem cell | Pluripotent stem cell marker |
| CD8 | 5.9 | T cell | Cytotoxic T cell marker |
| CD25 | 5.3 | Lymphocyte and macrophage | Lymphocyte activation |
| CD19 | 4.9 | B cell | B cell marker |
| CD4 | 4.4 | T cell | Helper T cell marker |
| CD326 | 3.6 | T cell, dendritic cell, epithelial cell | Epithelial cell marker unknown functions on immune cells |
| CD133-1 | 3.1 | Stem cell and endothelial cell | Stem cell marker |
1 Note: Since the cell types and possible biological functions of the exosomes studied are complicated with multi-cell types and multi-functions, the table only lists main cell types and functions of the exosomes.