Figure 7.

Fibrinogen complex is up-regulated in the cystic epithelia. (a,b) Representative images of fibrinogen immunohistochemistry in bile duct (upper panel) and liver parenchyma (lower panel) (a) and its quantification (b). n = 6 was used for each group. The immunohistochemistry analysis showed an up-regulation of fibrinogen through cystic epithelia. The samples corresponded to p12 group. Scale bars represents 100 µm. Bd means bile duct. Bars represent means ± SEM. Student’s t-test with two-tail was used and a value of p < 0.05 was considered significant. *** p < 0.001.