Figure 2.

A patient who was diagnosed with a right temporal lobe GBM. He underwent gross total resection and was subsequently treated with 60 Gy in 30 fractions with concurrent TMZ, followed by adjuvant TMZ. The RTOG approach was used to generate the target volumes. (A) T1 post-contrast axial MRI taken 48 h post gross total resection with a large postoperative cavity in the right temporal lobe; (B) T2 FLAIR axial MRI at the same level as (A) demonstrating significant surrounding edema; (C) Planning scan with PTV1 and PTV2 overlaid on (A). The area encompassed by the blue volume is receiving 46 Gy in 23 fractions, while the area encompassed by the red volume is receiving an additional 14 Gy in 7 fractions to a total dose of 60 Gy in 30 fractions.