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. 2022 Feb 19;11(2):423. doi: 10.3390/antiox11020423

Table 3.

Plasma fatty acids of healthy adults consuming whole peanuts or peanut butter in the ARISTOTLE study.

Plasma Fatty Acids (µg/mL) Whole Peanuts Peanut Butter p-Value WP vs. PB
Baseline Post-
Intervention
Post-Intervention–Baseline Baseline Post-
Intervention
Post-Intervention–Baseline
Myristic acid (C14:0) 15.46 ± 5.89 16.05 ± 7.74 0.59 ± 6.17 21.62 ± 16.81 19.72 ± 11.17 −2.76 ± 16.74 0.355
Palmitic acid (C16:0) 519 ± 275 541 ± 172 22.50 ± 285 643 ± 194 651 ± 165 8.12 ± 224 0.128
Palmitoleic acid (C16:1 n-7) 41.80 ± 14.78 47.26 ± 15.59 5.47 ± 14.99 55.01 ± 33.51 87.61 ± 132.38 28.80 ± 134.57 0.878
Stearic acid (C18:0) 190 ± 64.88 216 ± 150 25.65 ± 134 221 ± 46.80 212 ± 59.05 −18.01 ± 60.73 0.200
Vaccenic acid (C18:1 n-7) 32.24 ± 12.04 40.50 ± 10.08 8.26 ± 12.61 49.31 ± 16.46 78.38 ± 124 25.66 ± 123 0.474
Oleic acid (C18:1 n-9) 469 ± 169 544 ± 143 74.45 ± 135 691 ± 155 669 ± 207 −51.38 ± 203 0.040
Linoleic acid (C18:2 n-6) 757 ± 272 886 ± 215 129 ± 186 999 ± 194 982 ± 280 −60.04 ± 325 0.049
Alpha-linolenic acid (C18:3 n-3) 22.35 ± 53.82 8.53 ± 4.23 −13.82 ± 54.10 13.48 ± 9.92 11.56 ± 4.25 −2.43 ± 8.75 0.630
Gamma-linolenic acid (C18:3 n-6) 6.47 ± 4.48 8.41 ± 4.24 * 1.94 ± 3.64 10.12 ± 4.48 53.23 ± 204 40.79 ± 201 0.065
Arachidic acid (C20:0) 2.54 ± 1.32 3.06 ± 1.03 * 0.51 ± 1.51 3.06 ± 1.01 4.23 ± 1.58 * 1.12 ± 1.66 0.264
Eicosenoic acid (C20:1 n-9) 7.39 ± 7.66 6.63 ± 3.03 −0.76 ± 8.65 9.65 ± 7.77 40.59 ± 88.16 29.17 ± 86.44 0.378
Eicosadienoic acid (C20:2 n-6) 8.30 ± 8.90 7.75 ± 2.70 −0.55 ± 8.84 9.25 ± 3.29 8.52 ± 3.57 −1.11 ± 4.27 0.148
Eicosapentanoic acid (C20:5 n-3) 25.60 ± 20.54 24.69 ± 9.91 −0.91 ± 19.11 28.04 ± 19.65 44.93 ± 50.75 14.94 ± 53.92 0.235
Arachidonic acid (C20:4 n-6) 321 ± 159 202 ± 51.45 * −119 ± 120 222 ± 59.51 214 ± 75.14 −17.21 ± 80.51 0.062
Behenic acid (C22:0) 2.09 ± 1.03 4.66 ± 1.69 * 2.57 ± 1.71 2.63 ± 1.51 5.33 ± 1.52 * 2.58 ± 2.26 0.953
Docosatetraenoic acid (C22: 4 n-6) 17.78 ± 16.92 16.21 ± 5.42 −1.57 ± 18.51 18.76 ± 3.19 17.99 ± 3.22 −1.54 ± 5.67 0.062
Docosapentaenoic acid (C22:5 n-3) 21.97 ± 13.64 20.15 ± 4.45 −1.82 ± 15.63 22.68 ± 5.08 22.21 ± 5.14 −1.44 ± 7.35 0.431
Docosahexaenoic acid (C22:6 n-3) 69.42 ± 25.55 81.06 ± 22.47 11.65 ± 30.77 85.65 ± 33.33 92.80 ± 38.31 3.12 ± 44.40 0.474
Lignoceric acid (C24:0) 3.45 ± 0.77 9.28 ± 3.93 * 5.83 ± 3.81 3.93 ± 2.16 11.18 ± 4.02 * 6.93 ± 4.18 0.318
Tetracosenoic acid (C24:1 n-9) 11.44 ± 6.06 11.31 ± 3.68 −0.13 ± 8.00 13.34 ± 3.01 13.09 ± 5.74 −0.82 ±7.51 0.431
SFAs 755 ± 215 769 ± 351 12.65 ± 255 854 ± 254 895 ± 214 39.50 ± 204 0.990
 VLCSFAs 8.09 ± 2.54 17.00 ± 5.70 * 8.92 ± 5.37 9.62 ± 3.48 20.73 ± 5.55 * 11.11 ± 5.69 0.157
MUFAs 563 ± 185 650 ± 167 87.29 ± 152 819 ± 199 889 ± 306 66.26 ± 293 0.507
PUFAs 1240 ± 847 1247 ± 273 7.37 ± 844 1402 ± 232 1439 ± 253 37.11 ± 243 0.222
Total fatty acids 2558 ± 949 2666 ± 663 107 ± 615 3116 ± 593 3043 ± 907 66.88 ± 539 0.419

Data are expressed as mean ± standard deviation (SD). WP: whole peanuts; PB: peanut butter; SFAs: saturated fatty acids; VLCSFAs: very long chain saturated fatty acids; MUFAs: monounsaturated fatty acids; PUFAs: polyunsaturated fatty acids. p-values WP vs. PB refer to differences between whole peanut and peanut butter consumers regarding changes in fatty acid levels (post-intervention value minus the baseline value) calculated by Wilcoxon rank-sum tests. p-values < 0.05 were considered significant and are shown in bold. *: refers to significant differences between baseline and 6 months (post-intervention) results within each group, assessed by the Wilcoxon signed-rank test.