Table 3.
Effect of miconazole, sulfasalazine and their combination on relative colon weight, W/L ratio and lesion score in AA-induced UC.
| Group | Relative Colon Weight (g) | W/L Ratio (g/cm) | Lesion Score |
|---|---|---|---|
| NC | 0.34 b ± 0.04 | 0.071 b ± 0.008 | 0 ± 0 |
| UC | 0.65 a ± 0.06 | 0.133 a ± 0.01 | 3.52 ± 0.19 |
| MIC-20 | 0.62 a ± 0.03 | 0.129 a ± 0.007 | 2.57 ± 0.20 |
| MIC-40 | 0.53 a ± 0.01 | 0.102 ab ± 0.004 | 1.71 ± 0.29 |
| SSZ-100 | 0.53 a ± 0.02 | 0.102 ab ± 0.005 | 1.86 ± 0.26 |
| MIC + SSZ | 0.53 a ± 0.02 | 0.106 ab ± 0.002 | 1.43 ± 0.20 |
Each group’s values are expressed as the mean ± SEM of seven animals. a Significantly different at p ≤ 0.05 from the negative control (NC) values. b Significantly different at p ≤ 0.05 from the ulcerative colitis control (UC) values.