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(A): Overlap of CTX-M-1 (dark blue) and CTX-M-151 (light green) three-dimensional (3D) structures. In red, residues highlight the extra 13 amino acids of CTX-M-151 in comparison with CTX-M-1. (B): The Omega loop (active site), common to all CTX-M enzymes, is represented in orange for CTX-M-1 and in purple for CTX-M-151, with their respective sequences.
