Figure 3.
Effect of indomethacin (A,B) and L-NAME (C,D) on CSE relaxations in precontracted carotid and iliac artery segments from female adult rats. Relaxation is expressed as percentage of maximal contraction with NA (10−7 M). Data represent the mean ± SEM; n indicates the number of segments from 3–4 different rats per group. Statistical analysis was per-formed by 2-way-ANOVA considering concentration and drugs (CSE or CSE + Indomethacin/+L-NAME) as factors. The p-value was extracted of the interaction term of the ANOVA. CSE; cocoa shell extract; +E, endothelium positive segments.