Table 1.
Comparison of EC50 values and maximal relaxation to ACh and CSE in carotid and iliac artery segments with endothelium from female adult rats.
| Female Artery | EC50 ACh | EC50 CSE | p-Value | Max ACh (%) | Max CSE (%) | p-Value |
|---|---|---|---|---|---|---|
| Carotid (n = 9) |
7.46 × 10−7
[5.24 × 10−7; 3.13 × 10−6] |
7.26 × 10−10
[1.98 × 10−10; 1.07 × 10−7] |
<0.001 a | −69.71 ± 4.38 | −23.90 ± 3.92 | <0.001 b |
| Iliac (n = 8) |
5.51 × 10−7
[1.96 × 10−7; 1.48 × 10−6] |
4.16 × 10−9
[4.16 × 10−10; 2.44 × 10−6] |
0.045 a | −74.46 ± 4.79 | −21.92 ± 8.67 | <0.001 b |
EC50 values are shown as the median and interquartile range [Q1; Q3] and maximum relaxation (Max) as mean ± SEM, according to the distribution. The p-value was extracted by a Mann–Whitney or b Student’s t tests. ACh, Acetylcholine; CSE, cocoa shell extract; n indicates the number of segments.