Table 2.
Comparison of EC50 values and maximal relaxation to ACh and CSE in iliac artery segments with endothelium from male adult rats.
| Male Artery | EC50 ACh | EC50 CSE | p-Value | Max. Ach (%) | Max. CSE (%) | p-Value |
|---|---|---|---|---|---|---|
| Iliac (n = 6) | 3.04 × 10−7
[1.75 × 10−7; 1.22 × 10−6] |
1.20 × 10−9
[3.67 × 10−11; 9.45 × 10−9] |
0.002 a | −77.22 ± 4.40 | −22.41 ± 2.50 | <0.001 b |
EC50 values are shown as the median and interquartile range [Q1; Q3] and maximum relaxation (Max) as mean ± SEM, according to the distribution. The p-value was extracted by a Mann–Whitney or b Student’s t tests. ACh, Acetylcholine; CSE, cocoa shell extract; n indicates number of segments.