Table 3.
ACh and CSE responses in iliac arteries from old and adult female rats.
| Artery | Age | EC50 ACh | p-Value | Max ACh (%) | p-Value |
|---|---|---|---|---|---|
| Carotid | Old (n = 9) | 2.08 × 10−7 [1.52 × 10−7; 3.75 × 10−6] | 0.606 | −79.34 [−89.55; −58.29] | 0.307 |
| Adult (n = 5) | 3.31 × 10−7 [1.74 × 10−7; 7.64 × 10−7] | −87.21 [−90.44; −76.51] | |||
| Iliac | Old (n = 31) | 4.92 × 10−7 [8.50 × 10−8; 6.82 × 10−7] | 0.396 | −70.62 [−79.65; −33.93] | 0.886 |
| Adult (n = 18) | 4.93 × 10−7 [2.04 × 10−7; 2.37 × 10−6] | −68.09 [−83.70; −31.95] | |||
| Artery | Age | EC50 CSE | p -Value | Max CSE (%) | p -Value |
| Carotid | Old (n = 13) | 9.37 × 10−10 [2.87 × 10−10; 7.19 × 10−9] | 0.939 | −38.41 [−47.93; −20.23] | 0.307 |
| Adult (n = 8) | 5.96 × 10−10 [1.23 × 10−10; 1.23 × 10−7] | −25.57 [−32.70; −20.41] | |||
| Iliac | Old (n = 15) | 2.70 × 10−9 [3.47 × 10−10; 3.14 × 10−8] | 0.794 | −12.69 [−69.91; −6.04] | 0.879 |
| Adult (n = 9) | 2.15 × 10−9 [2.32 × 10−10; 1.63 × 10−6] | −16.84 [−41.45; −0.13] |
Data show median and interquartile range [Q1; Q3]. The p-value was extracted by Mann–Whitney test. ACh, Acetylcholine; CSE, cocoa shell extract; Max, maximal relaxation; n indicates the number of segments.