Table 4.
ACh and CSE responses in iliac arteries from old and adult male rats.
| Artery | Age | EC50 ACh | p-Value | Max ACh (%) | p-Value |
|---|---|---|---|---|---|
| Iliac | Old (n = 27) | 7.56 × 10−7 [1.16 × 10−7; 5.07 × 10−6] | 0.295 | −40.10 [−51.34; −18.00] | 0.016 |
| Adult (n = 9) | 4.47 × 10−7 [1.88 × 10−7; 9.13 × 10−7] | −71.45 [−84.04; −30.63] | |||
| Artery | Age | EC50 CSE | p -Value | Max CSE (%) | p -Value |
| Iliac | Old (n = 6) | 1.20 × 10−8 [2.65 × 10−9; 5.04 × 10−7] | 0.228 | −36.83 [−64.12; −25.27] | 0.005 |
| Adult (n = 8) | 2.40 × 10−9 [6.02 × 10−11; 2.39 × 10−8] | −21.05 [−24.67; −3.77] |
Data show median and interquartile range [Q1; Q3]. The p-value was extracted by Mann–Whitney test. ACh, Acetylcholine; CSE, cocoa shell extract; Max, maximal relaxation; n indicates the number of segments.