Table 5.
Parameter | Healthy (n = 29) | PAD (n = 40) | AAA (n= 40) | p-Value (Groups) |
---|---|---|---|---|
citH3 (ng/mL) | 292.3 (83.6) | 296.4 (221.7) | 353.2 (263.3) * | 0.046 (H/AAA) 0.734 (H/PAD) 0.070 (PAD/AAA) |
MPO (ng/mL) | 7.51 (3.20) | 12.11 (5.60) | 14.47 (11.74) | <0.001 (H/AAA) <0.001 (H/PAD) 0.021 (PAD/AAA) |
cfDNA (RU) | 0.277 (0.217) | 0.311 (0.190) § | 0.437 (0.737) § | 0.002 (H/AAA) 1.000 (H/PAD) 0.003 (PAD/AAA) |
oxPL/apoB (RU) | 6.33 (104.08) | 43.42 (92.50) | 0.00 (39.00) # | 0.197 (H/AAA) 0.181 (H/PAD) 0.001 (PAD/AAA) |
p-values refer to group comparisons between the healthy (H), abdominal aortic aneurysm (AAA) and peripheral artery occlusive disease (PAD) collectives by Mann–Whitney U test. cfDNA, cell-free DNA; citH3, citrullinated histone H3; MPO, myeloperoxidase; oxPL/apoB, oxidized phospholipid/apolipoprotein B-100 complexes; RU, relative units; * n = 38, § n = 30, # n = 39.