Table 9.
Effects of different doses of T. foenum-graecum seed extract on oxidative stress and lipid peroxidation in air pouch exudate.
| Treatment | Dose (mg/kg) | Myeloperoxidase (U/mg Protein) |
Malondialdehyde (nmol/mg Protein) |
Catalase (µmol H2O2/µg of Protein) | Superoxide Dismutase (U/mg of Protein) |
Total Oxidant Status (µM H2O2 Eq/g) | Total Antioxidant Status (µM Trolox Eq/g) |
|---|---|---|---|---|---|---|---|
| Control | - | 364 ± 1.54 | 5.84 ± 4.61 | 321.37 ± 2.87 | 4.39 ± 0.28 | 1.98 ± 0.45 | 6.35 ± 0.28 |
| Carrageenan | - | 647 ± 1.46 c | 14.46 ± 1.67 c | 218.38 ± 4.53 | 2.39 ± 0.21 | 13.21 ± 0.48 c | 0.28 ± 0.05 |
| T. foenum-graecum | 100 | 273 ± 2.01 | 13.28 ± 1.72 | 328.48 ± 2.23 | 4.39 ± 0.38 b | 9.98 ± 1.16 | 6.39 ± 0.60 a |
| 200 | 214 ± 1.03 | 9.99 ± 1.44 | 438.38 ± 3.99 | 5.92 ± 0.83 | 7.95 ± 0.71 | 6.54 ± 0.75 | |
| 400 | 184 ± 2.04 | 7.98 ± 1.14 | 647.29 ± 8.31 c | 6.20 ± 0.21 c | 6.47 ± 1.39 | 8.84 ± 1.25 b | |
| Dexamethasone | 20 | 173 ± 1.27 a | 8.30 ± 1.87 a | 438.58 ± 11.60 b | 7.31 ± 0.33 | 0.27 ± 0.32 | 13.68 ±1.99 c |
Each value is mean ± SD of three replicates; values with superscripts a, b and c are significant at 0.05, 0.01 and 0.001.