Table 10.
Effects of different doses of T. foenum-graecum seed extract on oxidative stress and lipid peroxidation in carrageenan-induced peritonitis.
| Treatment | Dose (mg/kg) | Myeloperoxidase (U/mg Protein) |
Malondialdehyde (nmol/mg Protein) |
Catalase (µmol H2O2/µg of Protein) | Superoxide Dismutase (U/mg of Protein) |
Total Oxidant Status (µM H2O2 Eq/g) | Total Antioxidant Status (µM Trolox Eq/g) |
|---|---|---|---|---|---|---|---|
| Control | - | 34 ± 0.24 | 1.45 ± 0.01 | 212.07 ± 2.97 | 1.39 ± 0.08 | 0.85 ± 0.01 | 1.65 ± 0.28 |
| Carrageenan | - | 177 ± 3.06 | 4.86 ± 0.27 | 109.48 ± 0.43 | 0.89 ± 0.16 | 0.22 ± 0.08 | 0.61 ± 0.05 |
| T. foenum-graecum | 100 | 31.42 ± 0.61 | 4.38 ± 0.21 b | 108.08 ± 0.13 a | 1.12 ± 0.81 a | 0.48 ± 0.06 | 1.09 ± 0.20 |
| 200 | 29.09 ± 0.23 | 3.99 ± 0.14 | 148.58 ± 0.69 | 1.16 ± 0.38 | 0.61 ± 0.01 | 1.54 ± 0.19 | |
| 400 | 18.53 ± 0.41 | 2.98 ± 1.14 | 205.29 ± 1.61 c | 1.21 ± 0.19 b | 0.98 ± 0.04 a | 1.49 ± 0.12 | |
| Dexamethasone | 20 | 15.98 ± 108.27 c | 1.10 ± 0.07 c | 201.18 ± 1.46 | 1.46 ± 0.35 | 0.97 ± 0.02 | 1.88 ± 0.67 b |
Each value is mean ± SD of three replicates; values with superscripts a, b and c are significant at 0.05, 0.01 and 0.001. Eq: Equivalent.