Table 3.
Heart weight-to-tibia length ratio (HW/TL), left ventricular end-diastolic dimensions (LVDD), left ventricular end-systolic dimensions (LVSD), septum diastolic diameter (IVSD), LV posterior wall diastolic diameter (LVPWD), left atrium diameter (LA) and aorta diameter (Ao) of Zucker Lean rats (ZL); Zucker Diabetic rats (ZDF); Zucker Diabetic rats treated with metformin (ZDF (M)); Zucker Diabetic rats fed with a CCB rich-diet (ZDF (CCB)), and Zucker Diabetic rats treated with metformin and fed with a CCB rich-diet (ZDF (CCB + M)). Data represent the means ± SD of 6–8 animals. Means in a row without a common letter differ, p < 0.05.
| ZL | ZDF | ZDF (M) | ZDF (CCB) | ZDF (CCB + M) | |
|---|---|---|---|---|---|
| HW/TL (g/cm) | 0.32 ± 0.02 a | 0.32 ± 0.01 a | 0.35 ± 0.03 a | 0.26 ± 0.01 b | 0.31 ± 0.01 a |
| LVDD (cm) | 0.73 ± 0.05 a | 0.76 ± 0.05 a | 0.75 ± 0.08 a | 0.65 ± 0.05 a | 0.68 ± 0.13 a |
| LVPWD (cm) | 0.22 ± 0.08 a | 0.20 ±0.05 a | 0.20 ± 0.05 a | 0.19 ± 0.04 a | 0.21 ± 0.04 a |
| LVSD (cm) | 0.40 ± 0.06 a | 0.46 ± 0.05 a | 0.38 ± 0.07 a | 0.39 ± 0.06 a | 0.39 ± 0.10 a |
| IVSD (cm) | 0.13 ± 0.05 a | 0.14 ± 0.05 a | 0.15 ± 0.05 a | 0.14 ± 0.05 a | 0.15 ± 0.05 a |
| Ao diameter (cm) | 0.33 ± 0.05 a | 0.23 ± 0.05 b | 0.32 ± 0.04 ab | 0.28 ± 0.08 ab | 0.28 ± 0.04 ab |
| LA diameter (cm) | 0.37 ± 0.08 a | 0.57 ± 0.08 b | 0.50 ± 0.05 b | 0.43 ± 0.07 ab | 0.49 ± 0.04 ab |