Table 2.
Diseases and functions analysis. Leukocytes movement, carcinoma and advanced malignant tumor resulted the most significant diseases and functions classes associated with modulated proteins. The proteins with their function and regulation after p53 knock-down are reported in the table.
| Diseases and Functions | ||
| Leukocytes movement | ||
| Protein | Regulation | Function |
| HSPB1 | Up-regulated | Decrease movement of leucocytes |
| PPIB | Down-regulated | Increase movement of leucocytes |
| ACTB | Down-regulated | Increase movement of leucocytes |
| HS90B | Down-regulated | Increase movement of leucocytes |
| ALB | Down-regulated | Increase movement of leucocytes |
| S10A4 | Down-regulated | Increase movement of leucocytes |
| Carcinoma | ||
| Protein | Regulation | Function |
| CATB | Up-regulated | Increase carcinoma |
| ALB | Down-regulated | Decrease carcinoma |
| CYTC | Down-regulated | Decrease carcinoma |
| SAA4 | Down-regulated | Decrease carcinoma |
| Advanced malignant tumour | ||
| Protein | Regulation | Function |
| CATB | Up-regulated | Increase advanced malignant tumour |
| BGH3 | Up-regulated | Increase advanced malignant tumour |
| ACTB | Down-regulated | Decrease advanced malignant tumour |
| CYTC | Down-regulated | Decrease advanced malignant tumour |
| SAA4 | Down-regulated | Increase advanced malignant tumour |