Table 1.
Comparison of analytical parameters for various formats of optical immunoassays and immunosensors used for hGH detection.
| Analytical System for hGH Detection | Linear or Dynamic Range | LOD | Sensitivity | Ref. |
|---|---|---|---|---|
| SPR-based immunosensors for the direct detection using reduced half antibody fragments | 10–720 nmol L−1 | 3.4 nmol L−1 | [25] | |
| SPR-based immunosensors for the direct detection using antibody immobilization via protein G | 3–9 nmol L−1 | 0.99 nmol L−1 | [26] | |
| SPR-based inhibition immunosensor format using surface modified with hGH | 18–542 ng mL−1 (0.82–24.6 nmol L−1) |
4 ng mL−1 (0.18 nmol L−1) |
[37] | |
| Sandwich ELISA, p-anti-hGH/hGH/anti-hGH-B/S-HRP, absorbance at 450 nm. | 1–25 ng mL−1 (0.046–1.14 nmol L−1) |
0.25 ng mL−1 (0.0114 nmol L−1) |
[38] | |
| Sandwich ELISA, anti-hGH/hGH/anti-hGH-B/S-HRP, absorbance at 450 nm. | 2.5–600 pg mL−1 1.1·10−4–0.027 nmol L−1 |
4 pg mL−1 (1.8·10−4 nmol L−1) |
[13] | |
| Sandwich ELISA, m-anti-hGH/hGH/m-anti-hGH-HRP, absorbance at 450 nm. | 0.5–50 ng mL−1 (0.023–2.27 nmol L−1) |
0.5 ng mL−1 (0.023 nmol L−1) |
[39] | |
| Indirect detection, MNPs-Au/m-anti-hGH/hGH/p-anti-hGH-B/S-HRP immunoassay, absorbance at 450 nm. | 0.1–5.0 nmol L−1 | 0.082 nmol L−1 | Current work |