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. 2022 Feb 9;11(2):271. doi: 10.3390/biology11020271

Table 1.

Plant viruses involved in m6A methylation or contained ALKB domains.

Virus. M6A-Related Proteins Summary of Knowledge References
Aalfalfa mosaic virus (AMV) ALKBH9B (At2g17970) The demethylation activity of atALKBH9B affected the infectivity of AMV by interacting with CP of AMV. Suppression of atALKBH9B increased the relative abundance of m6A in the AMVgenome, impairing the systemic invasion of the plant. Martinez-Perez et al., 2017
Cucumber mosaic virus (CMV) ALKBH9B (At2g17970) atALKBH9B does not have any effect on CMV infection. atALKBH9B does not interact with CP of CMV. Martinez-Perez et al., 2017
Tobacco mosaic virus (TMV) The potential demethylase XM_009801708 in Nicotiana tabacum. The overall level of m6A decreases after (TMV) infection in Nicotiana tabacum.
The expression level of XM_009801708 is increased upon TMV infection.
Zhurui et al., 2018
Grapevine virus A (GVA) Containing ALKB domain in viral genome Maintaining the integrity of the viral RNA genome through removal of deleterious RNA damage. Van den Born et al., 2008
Blueberry scorch virus (BlScV) Containing ALKB domain in viral genome Maintaining the integrity of the viral RNA genome through removal of deleterious RNA damage. Van den Born et al., 2008
Blackberry virusY (BVY) Containing ALKB domain in viral genome Maintaining the integrity of the viral RNA genome through removal of deleterious RNA damage. Van den Born et al., 2008
Little cherry virus (LChV-2) Containing ALKB domain in viral genome Not tested. Van den Born et al., 2008
Citric leave blotch virus (CLBV) Containing ALKB domain in viral genome Not tested. Van den Born et al., 2008
Chrysanthemum virus B (CVB) Containing ALKB domain in viral genome Not tested. Van den Born et al., 2008
Lily symptomless virus (LSV) Containing ALKB domain in viral genome Not tested. Van den Born et al., 2008
Apple stem pitting virus (ASPV) Containing ALKB domain in viral genome Not tested. Van den Born et al., 2008
Garlic latent virus (GLV) Containing ALKB domain in viral genome Not tested. Van den Born et al., 2008
Zygocactus virusX (ZVX) Containing ALKB domain in viral genome Not tested. Van den Born et al., 2008
Burdock mottle virus (BdMoV) Containing ALKB domain in viral genome Not tested. Kondo et al., 2013
Black raspberry necrosis virus (BRNV) Containing ALKB domain in viral genome Not tested. McGavin et al., 2010