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. 2022 Feb 14;11(2):382. doi: 10.3390/antiox11020382

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(a) Infarct size expressed as a percentage of the area at risk (left ventricle mass). Neither the CTRL nor IPA/NO-treated heart showed a significant difference in terms of necrosis after 2 h of reperfusion when compared to 1 h. n = 6 for each experimental group. Data are expressed as Average ± Standard Deviation. * p < 0.001, ns: non-significant. (b) Infarct size expressed as a percentage of the area at risk (left ventricle mass). IPA/NO protection is abolished by co-infusion of a specific inhibitor of PKC translocation. N = 6 for each experimental group. Data are expressed as Average ± Standard Deviation. * p < 0.001, ns = p > 0.05.