Table 2.

Reporting odds ratio of ICSRs with ADRs belonging to the SOCs “General disorders and administration site conditions”, “Blood and lymphatic system disorders”, “Musculoskeletal and connective tissue disorders” and “Investigations”, for the comparison of filgrastim versus pegfilgrastim.

ICSRs	ROR (95% CI)	p Value
General disorders and administration site conditions	1.14 (1.06–1.21)	<0.0001
Blood and lymphatic system disorders	0.75 (0.70–0.80)	<0.0001
Musculoskeletal and connective tissue disorders	1.21 (1.18–1.32)	<0.0001
Investigations	1.01 (0.93–1.10)	0.78

Abbreviations: ICSRs = Individual Case Safety Reports; ADRs = adverse drug reactions; SOCs = System Organ Classes; ROR = reporting odds ratio; CI = confidence interval.