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The immunosuppressive effects of oncometabolites. TAMs—tumor-associated macrophages; VCAM1—vascular cell adhesion molecule 1; IL—interleukin; TME—tumor microenvironment; PD1—programmed cell death 1; PD-L1—programmed cell death ligand 1; CTLA-4—cytotoxic T-cell antigen 4; TIM-3—T-cell immunoglobulin and mucin domain 3; LAG3—lymphocyte activation gene 3 protein; NK—natural killer; TNF—tumor necrosis factor.
