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. 2022 Jan 27;10(2):292. doi: 10.3390/biomedicines10020292

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) From an immunotherapy trial dataset (GSE121810), the ratio of M1/M2 macrophage and the mean value of RSI in neoadjuvant and adjuvant arm are compared. p-value was estimated with analysis of variance. (B) From the Glioma Longitudinal Analysis Consortium (GLASS), overall survival for recurrent glioblastoma population is compared, stratified by M2 macrophage and RSI status. p-value was estimated by log-rank test. (C) Comparison of overall survival between M2 macrophage-low and RSI-low group versus other population in recurrent glioblastoma. Abbreviations: M1, M1 macrophage; M2, M2 macrophage; RSI, radiosensitive index.