Table 1.
Role of transcription factors (TFs) in tomato response to biotic stresses.
| TF Family | TF Target Gene | Effect | Method | Ref. |
|---|---|---|---|---|
| WRKY | SlDRW1 | - Gene expression significantly induced by Botrytis cinerea. - Silencing increase severity of disease caused by B. cinerea. |
VIGS | [79] |
| SpWRKY1 | - Overexpression increase resistance to Phytophthora infestans. | Expression vector | [80] | |
| SpWRKY3 | - Gene expression significantly induced by Phytophthora infestans. - Silencing impaired the resistance to P. infestans. - Overexpression increase resistance to P. infestans. |
VIGS and expression vector | [81] | |
| SlWRKY8, SlWRKY23, SlWRKY39, SlWRKY53, SlWRKY80, SlWRKY81 | - Up-regulated genes expression in response to Pseudomonas syringae (Pst) pv. tomato DC3000 infection. | - | [82] | |
| SlWRKY39 | - Overexpressing increased resistance to P. syringae. | Expression vector | [83] | |
| SlWRKY72a, SlWRKY72b | - Up-regulated during root-knot nematodes (RKN) disease resistance mediated by the R gene Mi-1. - Silencing resulted in a reduction of Mi-1-mediated resistance and basal defense against RKN. |
VIGS | [84] | |
| SlWRKY45 | - Overexpression enhanced tomato susceptibility to RKN | Expression vector | [85] | |
| SolyWRKY41, SolyWRKY42, SolyWRKY53, SolyWRKY54, SolyWRKY80, SolyWRKY8 | - Genes responsive to Tomato yellow leaf curly virus (TYLCV) infection. - Silencing of SolyWRKY41 and SolyWRKY54 decrease accumulation of TYLCV DNA. |
VIGS | [86] | |
| NAC | SlNAP1 | - Overexpressing enhanced defense against Pst DC3000 and Ralstonia solanacearum. | Expression vector | [87] |
| SlSRN1 | - Gene expression induced by infection with B. cinerea and Pst DC3000. - Silencing increased severity of disease caused by B. cinerea. |
VIGS | [88] | |
| SlNAC1 | - Upregulated gene expression during Pst DC3000 infection. | - | [89] | |
| SlNAC1 | - Overexpression enhanced the accumulation of Tomato leaf curl virus (TLCV) DNA. | Expression vector | [90] | |
| AP2/ERF | ERF-3 | - Upregulated gene expression to Alternaria solani infection, using a resistant genotype. | - | [91] |
| ERF-2 | - Silencing revealed aggravated diseases symptoms caused by Stemphylium lycopersici. | VIGS | [92] | |
| SlSHINE3 | - Silencing revealed higher sensitivity to B. cinerea. - Overexpression revealed resistance to B. cinerea and to Xanthomonas campestris pv. vesicatoria infection. |
Not referred | [93] | |
| bHLH | bHLH132 | - Transcriptionally highly induced by Xanthomonas euvesicatoria. - Silencing enhanced susceptibility to X. euvesicatoria. |
Expression vector | [71] |
| MYC2 | - Knockout aggravated the B. cinerea disease symptoms. | CRISPR/Cas9 | [94] | |
| bZIP | SlAREB1 | - Overexpression up-regulate several defense genes associated with biotic stress. | Expression vector | [95] |